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Monoclonal antibodies are artificial proteins that are similar to antibodies or immunoglobulins, namely substances that form human immunity. These artificial antibodies have many functions in the medical world, from helping with diagnosis to treating various diseases.
Monoclonal antibodies have been used to treat various diseases, ranging from autoimmune diseases to several types of cancer. Not only that, monoclonal antibodies can also be used to help treat infectious diseases, especially viral infections.
Despite offering many benefits, it is important to remember that the use of monoclonal antibodies should be done under medical supervision, considering the potential side effects and allergic reactions that may occur.
Monoclonal Antibodies and Their Benefits
Monoclonal antibodies often used in the medical world for various purposes, including:
Diagnosing certain conditions
This artificial protein can be used to diagnose various medical conditions, such as:
- Detect the presence of certain antigens in blood or tissue body
- Detecting pregnancy
- Diagnosing certain diseases, such as hormonal disorders, cancer, and sexually transmitted infections
Treating diseases
Not only for diagnosing diseases, monoclonal antibodies are also generally used to treat various diseases, such as:
- Cancer
- Autoimmune diseases, such as lupus and rheumatoid arthritis
- Viral infections, for example HIV, hepatitis B, and hepatitis C
- Cytokine storm due to COVID-19
- Allergies
- Asthma
- Eczema or dermatitis, for example atopic dermatitis
- Osteoporosis
- Inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis
- Allergic rhinitis
In addition, monoclonal antibodies can also be used in patients undergoing transplant surgery or grafting certain body organs, such as kidney or liver transplants. This protein is given to reduce the patient's immune response to the donor organ received.
Monoclonal Antibodies and Their Procedures
Antibodies can actually be produced naturally by the body's immune system. However, this substance sometimes cannot work optimally or is not produced enough due to certain diseases. Instead, the body needs artificial antibodies or monoclonal antibodies that can work like natural antibodies. These monoclonal antibodies are produced in the laboratory.
Monoclonal antibodies are usually given to patients by injection intravenous (IV), namely an injection method that is carried out by inserting medication through a vein. This drug can be administered by a doctor or nurse, according to the doctor's direction.
Apart from intravenous injection, several types of monoclonal antibody drugs are also administered. can be given by injection subcutaneously or into fat tissue. This injection can be given into the stomach, arm, or thigh.
Several types monoclonal antibody drugs that can be given by doctors include:
- Adalimumab
- Golimumab
- Infliximab
- Rituximab
- Tocilizumab
Before giving monoclonal antibodies, the doctor will first determine whether the patient's condition formerly. Administration of this drug usually needs to be postponed in patients who are pregnant or who suffer from certain conditions, such as blood pressure that is too low, sepsis, and severe heart failure.
Monoclonal Antibodies and Their Risks
Just like other drugs, antibodies Monoclonals can also cause various side effects. The following are some of the side effects of monoclonal antibodies that can occur:
- Fever
- fatigue
- Nausea
- Vomiting
- Diarrhea
- Low blood pressure
In addition , monoclonal antibodies can also cause more serious side effects and complications, such as allergic drug reactions, anaphylaxis, bleeding, red rashes on the skin, and heart and lung problems. Therefore, the use of this drug must always be under the supervision of a doctor.
Please remember that how often a patient requires a monoclonal antibody procedure will depend greatly on on the type of drug used and the condition to be treated.
If you have other questions about monoclonal antibodies, don't hesitate to consult a doctor via Chat with a Doctor. Later, the doctor will provide more complete information that suits what you need.
Label : Health
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