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High SGPT can be determined from a blood test. Serum Glutamic-Pyruvic Transaminase (SGPT) levels that are higher than normal are often not dangerous and do not require medical treatment. However, high SGPT levels can also be associated with impaired liver function so it is important to be aware of the symptoms.
Serum Glutamic-Pyruvic Transaminase (SGPT) is an enzyme which is mostly found in the liver. This enzyme supports the function of the liver in breaking down protein so that it is more easily absorbed by the body and processed into energy.
Increased SGPT levels can also be caused by harmless conditions, but can also be associated with problems with liver function because they are found in liver function examination. So, in order to know when to be alert when SGPT is high, there are signs and symptoms that need to be recognized.
Causes of High SGPT
Normal SGPT levels range from 7–56 units per liter. Levels of this enzyme are usually lower in elderly people. High SGPT values can be temporary or permanent depending on the cause.
The following are various causes of high SGPT ranging from dangerous to temporary:
1. Liver dysfunction
Some conditions liver dysfunction, such as hepatitis, liver cirrhosis, fatty liver, or liver cancer, will be characterized by high SGPT levels.
Inflammation of the liver can trigger damage to the cells in it, disrupting liver function. This condition causes more SGPT enzymes to enter the bloodstream. If caused by impaired liver function, SGPT levels will increase to 7-50 times the normal limit.
2. Obesity
Obesity can trigger liver damage due to fat accumulation redundant. This condition makes the liver store more fatty acids, making it more susceptible to inflammation. When the liver starts to experience problems, the results of liver function tests can show high SGPT values.
3. Diabetes
High blood sugar levels experienced by diabetes sufferers can cause damage to blood vessels, tissues and body organs, including the liver which plays a role in the production and storage of glucose .
When diabetes has damaged the liver, liver function will decrease and trigger chronic liver disease which is characterized by increased SGPT levels.
4. Consuming certain medications
Some drugs can trigger liver function disorders, such as hepatitis. Moreover, if the drug is consumed long term or excessively. The liver also plays a role in breaking down drugs, but this process can occur more slowly in some people, causing liver damage.
There are various drugs that trigger high SGPT values, namely statins, erythromycin, or pain relievers.
5. Strenuous exercise
Strenuous exercise, such as running a marathon, will reduce blood and oxygen flow to the liver. This condition causes liver enzyme levels to increase, making the SGPT value high. However, the increase in SGPT due to exercise does not exceed normal limits and will return to its original level after 7 days of rest.
However, high SGPT levels can also last longer or persist in athletes who continuously exercise vigorously.
6. Menstrual cycle
Increased SGPT can occur during the menstrual cycle. High SGPT values are often found in the follicular phase, namely the first phase of the menstrual cycle until ovulation occurs. Changes in SGPT values are triggered by changes in hormone levels during the menstrual cycle.
When progesterone levels increase in the luteal phase, namely the phase after ovulation until the next menstruation, the SGPT value tends to decrease and return to normal before menstruation.
Symptoms of High SGPT to Watch Out for
High SGPT levels are often only discovered during liver function examinations or blood tests routine. In non-hazardous causes, an increase in SGPT of 2-3 times generally does not show typical symptoms.
However, high SGPT associated with liver damage will cause the following symptoms:
- Nausea and vomiting
- Decreased appetite
- Tired easily
- Yellow skin and eyes
- The stomach is swollen and sometimes accompanied by pain
- Swollen ankles and legs
- Dark colored urine
- Light colored stools
- Constantly itchy skin
High SGPT levels can be reduced by consuming foods low in carbohydrates and saturated fat, and consuming lots of foods that contain folate, such as spinach, bananas, papaya, and beetroot. Consuming healthy foods needs to be balanced with regular blood checks from a doctor to monitor healthy liver function.
If symptoms of high SGPT due to impaired liver function appear, especially if you have a history of obesity, diabetes, hepatitis, and alcohol addiction, you should consult a doctor.
The doctor may recommend supporting examinations to determine the cause of the symptoms you are experiencing. That way, the treatment given will be more precise and appropriate.
Label : Health
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